Article
Description of lymphocyte and cytokine profiles in individuals with acute myeloid leukemia associated with FLT3-ITD and NPM1 mutation status.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) - 1 Mar 2025
Reis Rogério, Müller Gabriel S, Santos Mariane M, Santos Allan S, Santos Herbert, Santos Lorene S, Lopes Bruno A, Trindade Soraya C, Meyer Roberto J, Freire Songelí M
Abstract excerpt
The pathogenesis of acute myeloid leukemia (AML) involves mutations in genes such as FLT3 and NPM1 , which are also associated with the prognosis of the disease. The immune system influences disease progression, but the mechanisms underlying the interaction between the immune system and AML are not clear. In this study, the profiles of lymphocytes and cytokines were described in individuals with AML stratified by...
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