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Individualized lncRNA differential expression profile reveals heterogeneity of breast cancer

15 Jun 2021

Abstract excerpt

Long non-coding RNAs (lncRNAs) play key regulatory roles in breast cancer. However, population-level differential expression analysis methods disregard the heterogeneous expression of lncRNAs in individual patients. Therefore, we individualized lncRNA expression profiles for breast invasive carcinoma (BRCA) using the method of LncRNA Individualization (LncRIndiv). After evaluating the robustness of LncRIndiv, we...

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PMID: 34131286
DOI: 10.1038/s41388-021-01883-6

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