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Redefinition of the human mast cell transcriptome by deep-CAGE sequencing

27 Mar 2014

Abstract excerpt

Mast cells (MCs) mature exclusively in peripheral tissues, hampering research into their developmental and functional programs. Here, we employed deep cap analysis of gene expression on skin-derived MCs to generate the most comprehensive view of the human MC transcriptome ever reported. An advantage is that MCs were embedded in the FANTOM5 project, giving the opportunity to contrast their molecular signature...

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PMID: 24671954
DOI: 10.1182/blood-2013-02-483792

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