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Article

A heterogeneous tumor immune microenvironment of uncommon epidermal growth factor receptor mutant non-small cell lung cancer.

Cancer science - 1 Sept 2024

Zhang Chong, Yang Liangwei, Zhao Weidi, Zhu Huangkai, Shi Shuo, Chen Songan, Wang Guoqiang, Li Bing, Zhao Guofang

Abstract excerpt

Common epidermal growth factor receptor (EGFR) mutations are usually not considered for immunotherapy in non-small cell lung cancer (NSCLC) due to poor efficacy. However, whether uncommon EGFR mutations are suitable for immunotherapy has not been thoroughly studied. Thus, we explored the tumor immune microenvironment (TME) features in uncommon EGFR mutant NSCLC. In this study, a total of 41 patients with EGFR...

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Identifiers

PMID: 38890815
DOI: 10.1111/cas.16253
PMCID: PMC11462928

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