Article
The rod cell, a small form of Candida albicans, possesses superior fitness to the host gut and adaptation to commensalism.
Acta biochimica et biophysica Sinica - 9 Sept 2024
Xu Yinxing, Zhu Wencheng, Dai Baodi, Xiao Hui, Chen Jiangye
Abstract excerpt
Candida albicans deploys various morphological forms through complex switching mechanisms, ensuring its survival and thriving as a commensal or pathogen in vastly different human niches. In this study, we demonstrate that a novel ''rod'' morphological form of C. albicans coexists and is interchangeable with previously reported white, gray, and opaque forms, constituting a tetra-stable phenotypic switching system....
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