Phenotypic Switching and Filamentation in Candida haemulonii, an Emerging Opportunistic Pathogen of Humans.

doi:10.1128/Spectrum.00779-21

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Article

Phenotypic Switching and Filamentation in Candida haemulonii, an Emerging Opportunistic Pathogen of Humans.

Microbiology spectrum - 22 Dec 2021

Deng Yuchen, Li Shuaihu, Bing Jian, Liao Wanqing, Tao Li

Abstract excerpt

Phenotypic plasticity is a common strategy adopted by fungal pathogens to adapt to diverse host environments. Candida haemulonii is an emerging multidrug-resistant human pathogen that is closely related to Candida auris. Until recently, it was assumed that C. haemulonii is incapable of phenotypic switching or filamentous growth. In this study, we report the identification of three distinct phenotypes in C....

Topics

Adaptation, Physiological
Aspartic Acid Proteases
Biological Variation, Population
Candida
Candidiasis
Copper Sulfate
Gene Expression Regulation, Fungal
Hot Temperature
Humans
Phenotype

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Identifiers

PMID: 34878301
DOI: 10.1128/Spectrum.00779-21
PMCID: PMC8653834

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