Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Discovery and functional investigation of BMP4 as a new causative gene for human congenital heart disease

1 Jan 2024

Abstract excerpt

OBJECTIVE: mutation underlying human CHD and explore its functional impact. METHODS: induced by BMP4 were measured by employing a dual-luciferase analysis system. RESULTS: , two genes whose expression is lost in CHD. CONCLUSION: as a new gene predisposing to human CHD, allowing for improved prenatal genetic counseling along with personalized treatment of CHD patients.

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Congenital heart defects research
Share to Congenital Heart Disease Studies
Share to Tissue Engineering and Regenerative Medicine

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Identifiers

PMID: 38883374
DOI: 10.62347/dgcd4269

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 9 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Discovery and functional investigation of BMP4 as a new causative gene for human congenital heart diseasePMID 38883374Read ↗

Functionally significant, novel variants of <i>BMP4</i> are associated with isolated congenital heart diseaseSemantic proximity Read ↗

Characterization of human bone morphogenetic protein gene variants for possible roles in congenital heart disease.Semantic proximity Read ↗

Implication of novel variants of <i>BMP2</i> in isolated congenital heart disease: Functional characterization by <i>in silico</i> and <i>invitro</i> approachesSemantic proximity Read ↗

SMAD4 loss-of-function mutation predisposes to congenital heart disease.Semantic proximity Read ↗

SMAD1 Loss‐of‐Function Variant Responsible for Congenital Heart DiseaseSemantic proximity Read ↗

BMP signaling in congenital heart disease: New developments and future directionsSemantic proximity Read ↗

Deciphering the functional association of novel variants of <i>BMP7</i> in isolated congenital heart disease by integrating <i>in vitro</i> and <i>in silico</i> approachesSemantic proximity Read ↗

Common variations in BMP4 confer genetic susceptibility to sporadic congenital heart disease in a Han Chinese population.Semantic proximity Read ↗

TRANSCRIPTION FACTORS AND CONGENITAL HEART DEFECTSSemantic proximity Read ↗

The Human Bone Morphogenetic Protein 4 (BMP-4) Gene: Molecular Structure and Transcriptional RegulationSemantic proximity Read ↗

A new mutation in the hepcidin promoter impairs its BMP response and contributes to a severe phenotype in HFE related hemochromatosis.Semantic proximity Read ↗

The association between BMP4 gene polymorphism and its serum level with the incidence of LVH in hypertensive patients.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.