Article
The Genetic Diversity of HIV-1 Quasispecies Within Primary Infected Individuals.
AIDS research and human retroviruses - 1 May 2020
Liu Yongjian, Jia Lei, Su Bin, Li Hanping, Li Zhen, Han Jingwan, Zhang Yu, Zhang Tong, Li Tianyi, Wu Hao, Li Jingyun, Li Lin
Abstract excerpt
HIV has remarkable genetic diversity among populations. The diversity has critical impacts on transmission, immune escape, pathogenesis, and clinical management. HIV-1 diversity originates from frequent mutation and recombination during reverse transcription. This work focuses on the quasispecies genetic dynamics within individuals with primary infections. Eleven men who have sex with men from the Beijing PRIMO...
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