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Article

Causal association of obesity with epigenetic aging and telomere length: a bidirectional mendelian randomization study

12 Mar 2024

Abstract excerpt

BACKGROUND: In observational studies, there exists an association between obesity and epigenetic age as well as telomere length. However, varying and partially conflicting outcomes have notably arisen from distinct studies on this topic. In the present study, two-way Mendelian randomization was used to identify potential causal associations between obesity and epigenetic age and telomeres. METHODS: A genome-wide...

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Share to Epigenetics and DNA Methylation
Share to Genetic Associations and Epidemiology
Share to Telomeres, Telomerase, and Senescence

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PMID: 38475782
DOI: 10.1186/s12944-024-02042-y

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