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Article

Neural indices of heritable impulsivity: Impact of the COMT Val158Met polymorphism on frontal beta power during early motor preparation.

Biological psychology - 1 Sept 2024

Happer Joseph P, Beaton Lauren E, Wagner Laura C, Hodgkinson Colin A, Goldman David, Marinkovic Ksenija

Abstract excerpt

Studies of COMT Val158Met suggest that the neural circuitry subserving inhibitory control may be modulated by this functional polymorphism altering cortical dopamine availability, thus giving rise to heritable differences in behaviors. Using an anatomically-constrained magnetoencephalography method and stratifying the sample by COMT genotype, from a larger sample of 153 subjects, we examined the spatial and...

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Identifiers

PMID: 38862067
DOI: 10.1016/j.biopsycho.2024.108826

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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