Article
Whole Genome Sequencing of Mycobacterium tuberculosis under routine conditions in a high-burden area of multidrug-resistant tuberculosis in Peru.
PloS one - 1 Jan 2024
Puyén Zully M, Santos-Lázaro David, Vigo Aiko N, Cotrina Vidia V, Ruiz-Nizama Nathaly, Alarcón Miriam J, Asto Belisa, Huamán Teresa, Moore David A J
Abstract excerpt
Whole Genome Sequencing (WGS) is a promising tool in the global fight against tuberculosis (TB). The aim of this study was to evaluate the use of WGS in routine conditions for detection of drug resistance markers and transmission clusters in a multidrug-resistant TB hot-spot area in Peru. For this, 140 drug-resistant Mycobacterium tuberculosis strains from Lima and Callao were prospectively selected and processed...
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