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Genotypic clustering does not imply recent tuberculosis transmission in a high prevalence setting: A genomic epidemiology study in Lima, Peru

2018-09-16

Abstract excerpt

<h4>Background</h4> Whole genome sequencing (WGS) can elucidate Mycobacterium tuberculosis (Mtb) transmission patterns but more data is needed to guide its use in high-burden settings. In a household-based transmissibility study of 4,000 TB patients in Lima, Peru, we identified a large MIRU-VNTR Mtb cluster with a range of resistance phenotypes and studied host and bacterial factors contributing to its spread....

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Identifiers and source

Literature Corpus work
90535439-6bcb-5837-bdf1-b0ef6ca87c34
DOI
10.1101/418202
Open publication

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