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Estimating genetic variance contributed by a quantitative trait locus: removing nuisance parameters.

Genetics - 7 Aug 2024

Xu Shizhong

Abstract excerpt

The main objective of mapping quantitative trait loci (QTL) and genome-wide association studies (GWAS) is to identify and locate QTLs on the genome. Estimating the sizes of QTL is equally important as identifying the QTLs. The size of a QTL is often measured by the QTL variance, or the proportion of phenotypic variance explained by the QTL, known as the QTL heritability. The reported QTL heritability is biased...

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PMID: 38861387
DOI: 10.1093/genetics/iyae095

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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