Article
Gene polymorphism of transforming growth factor-β1 in Egyptian patients with type 2 diabetes and diabetic nephropathy.
Acta biochimica et biophysica Sinica - 1 Apr 2013
El-Sherbini Sherif M, Shahen Samar M, Mosaad Youssef M, Abdelgawad Mohamed S, Talaat Roba M
Abstract excerpt
Role of the transforming growth factor-β1 (TGF-β1) gene polymorphisms located at codons 10 and 25 in the genetic predisposition to type 2 diabetes (T2D) and in diabetic nephropathy (DN) in Egyptian patients was investigated. A case control study was done for 99 unrelated Egyptian patients with T2D (50 DN(-) and 49 DN(+)) and 98 age- and sex-matched healthy controls. TGF-β1 T869C (codon 10) and G915C (codon 25)...
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