Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

An automated, high-resolution phenotypic assay for adult Brugia malayi and microfilaria.

Scientific reports - 7 Jun 2024

Kalwa Upender, Park Yunsoo, Kimber Michael J, Pandey Santosh

Abstract excerpt

Brugia malayi are thread-like parasitic worms and one of the etiological agents of Lymphatic filariasis (LF). Existing anthelmintic drugs to treat LF are effective in reducing the larval microfilaria (mf) counts in human bloodstream but are less effective on adult parasites. To test potential drug candidates, we report a multi-parameter phenotypic assay based on tracking the motility of adult B. malayi and mf in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Anthelmintics
Share to Phenotype

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Source

Open in PubMed Open full text

Identifiers

PMID: 38849355
DOI: 10.1038/s41598-024-62692-x
PMCID: PMC11161659

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

An automated, high-resolution phenotypic assay for adult Brugia malayi and microfilaria.PMID 38849355Read ↗

A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discoverySemantic proximity Read ↗

A multi-dimensional, time-lapse, high content screening platform applied to schistosomiasis drug discoverySemantic proximity Read ↗

Fast, automated measurement of nematode swimming (thrashing) without morphometry.Semantic proximity Read ↗

Megapixel camera arrays for high-resolution animal tracking in multiwell platesSemantic proximity Read ↗

Megapixel camera arrays enable high-resolution animal tracking in multiwell plates.Semantic proximity Read ↗

Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery.Semantic proximity Read ↗

Deep phenotypic profiling uncovers cryptic effects of antifilarial drugsSemantic proximity Read ↗

Automated scoring of nematode nictation on a textured backgroundSemantic proximity Read ↗

Robust tracking and quantification of<i>C. elegans</i>body shape and locomotion through coiling, entanglement, and omega bendsSemantic proximity Read ↗

Deep phenotypic profiling uncovers cryptic effects of antifilarial drugs.Semantic proximity Read ↗

Quantifying the mechanics of locomotion of the schistosome pathogen with respect to changes in its physical environmentSemantic proximity Read ↗

Geometric morphometrics to differentiate species and explore seasonal variation in three Mansonia species ( Diptera: Culicidae ) in central Thailand and their association with meteorological factorsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.