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Article

Novel Genetic Variants Associated with Primary Myocardial Fibrosis in Sudden Cardiac Death Victims.

Journal of cardiovascular translational research - 1 Dec 2024

Skarp Sini, Doedens Anne, Holmström Lauri, Izzi Valerio, Saarimäki Samu, Sliz Eeva, Kettunen Johannes, Pakanen Lasse, Kerkelä Risto, Pylkäs Katri, Huikuri Heikki V, Myerburg Robert J, Junttila Juhani

Abstract excerpt

Myocardial fibrosis is a common finding in victims of sudden cardiac death (SCD). Whole exome sequencing was performed in 127 victims of SCD with primary myocardial fibrosis as the only pathological finding. These cases are derived from the Fingesture study which has collected data from autopsy-verified SCD victims in Northern Finland. A computational approach was used to identify protein interactions in...

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Source

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Identifiers

PMID: 38848015
DOI: 10.1007/s12265-024-10527-5
PMCID: PMC11634914

Genes

SCD
CAPN1
UNC45A
UNC45B

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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