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Article

Combination of FLNC and JUP variants causing arrhythmogenic cardiomyopathy in an Iranian family with different clinical features.

BMC cardiovascular disorders - 23 Aug 2024

Mehdizadeh Kasra, Soveizi Mahdieh, Askarinejad Amir, Elahifar Amin, Masoumi Tannaz, Fazelifar Amir Farjam, Asadian Sanaz, Maleki Majid, Kalayinia Samira

Abstract excerpt

BACKGROUND: Arrhythmogenic cardiomyopathy (ACM) characterized by progressive myocardial loss and replacement with fibro-fatty tissue is a major cause of sudden cardiac death (SCD). In particular, ACM with predominantly left ventricular involvement, known as arrhythmogenic left ventricular cardiomyopathy (ALVC), has a poor prognosis. METHODS: The proband underwent whole-exome sequencing (WES) to determine the...

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Share to Arrhythmogenic Right Ventricular Dysplasia
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39180012
DOI: 10.1186/s12872-024-04126-0
PMCID: PMC11342628

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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