Article
Genetic variants associated with cardiac hypertrophy-related sudden cardiac death and cardiovascular outcomes in a Finnish population.
Heart (British Cardiac Society) - 23 Dec 2024
Doedens Anne, Skarp Sini, Holmström Lauri, Pakanen Lasse, Saarimäki Samu, Kerkelä Risto, Pylkäs Katri, Huikuri Heikki V, Junttila Juhani
Abstract excerpt
BACKGROUND: Hypertrophic cardiomyopathy is a common cause of non-ischaemic sudden cardiac death (SCD). Left ventricular hypertrophy (LVH) without cardiomyopathy-related myocardial disarray is a common autopsy finding and is often associated with prior hypertension in SCD subjects. Our aim was to investigate novel rare gene variants among SCD subjects with presumably hypertension-related LVH and myocardial...
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