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Article

Post-mortem whole-exome sequencing (WES) with a focus on cardiac disease-associated genes in five young sudden unexplained death (SUD) cases.

International journal of legal medicine - 1 Jul 2016

Neubauer Jacqueline, Haas Cordula, Bartsch Christine, Medeiros-Domingo Argelia, Berger Wolfgang

Abstract excerpt

Sudden death of healthy young adults in the absence of any medical reason is generally categorised as autopsy-negative sudden unexplained death (SUD). Approximately 30 % of all SUD cases can be explained by lethal sequence variants in cardiac genes causing disturbed ion channel functions (channelopathies) or minimal structural heart abnormalities (cardiomyopathies). The aim of this study was to perform...

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Source

Identifiers

PMID: 26846766
DOI: 10.1007/s00414-016-1317-4

Genes

DCHS1
KCNH2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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