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Article

Defining the Genomic Landscape of Diffuse Sclerosing Papillary Thyroid Carcinoma: Prognostic Implications of RET Fusions.

Annals of surgical oncology - 1 Sept 2024

Scholfield Daniel W, Fitzgerald Conall W R, Boe Lillian A, Eagan Alana, Levyn Helena, Xu Bin, Tuttle R Michael, Fagin James A, Shaha Ashok R, Shah Jatin P, Wong Richard J, Patel Snehal G, Ghossein Ronald, Ganly Ian

Abstract excerpt

BACKGROUND: Diffuse sclerosing papillary thyroid carcinoma (DSPTC) is an aggressive histopathologic subtype of papillary thyroid carcinoma. Correlation between genotype and phenotype has not been comprehensively described. This study aimed to describe the genomic landscape of DSPTC comprehensively using next-generation sequencing (NGS), analyze the prognostic implications of different mutations, and identify...

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Share to Endosomal Sorting Complexes Required for Transport
Share to Oncogene Proteins, Fusion

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proto-Oncogene Proteins B-raf

Share to Proto-Oncogene Proteins c-ret

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Share to Thyroid Cancer, Papillary

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PMID: 38847983
DOI: 10.1245/s10434-024-15500-9

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