Article
Genomic landscape of metastatic papillary thyroid carcinoma and novel biomarkers for predicting distant metastasis.
Cancer science - 1 Jun 2020
Lan Xiabin, Bao Hua, Ge Xinyang, Cao Jun, Fan Xiaojun, Zhang Qihong, Liu Kaihua, Zhang Xian, Tan Zhuo, Zheng Chuanming, Wang Ao, Chen Chao, Zhu Xin, Wang Jiafeng, Xu Jiajie, Zhu Xuhang, Wu Xue, Wang Xiaonan, Shao Yang, Ge Minghua
Abstract excerpt
Papillary thyroid carcinoma (PTC) is the most common malignancy of the thyroid gland, with a relatively high cure rate. Distant metastasis (DM) of PTC is uncommon, but when it occurs, it significantly decreases the survival of PTC patients. The molecular mechanisms of DM in PTC have not been systematically studied. We performed whole exome sequencing and GeneseeqPrime (425 genes) panel sequencing of the primary...
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