Article
What do cancer genetic providers want us to know about variant reclassification and recontact that we are not asking? A thematic analysis of open-ended survey responses.
Cancer - 15 Nov 2024
Brown Kerri, Ponton Marisel, Davidson Elenita, Arun Banu, Volk Robert J, Shete Sanjay, Peterson Susan K, Makhnoon Sukh
Abstract excerpt
BACKGROUND: Accurate variant classification and relaying reclassified results to patients is critical for hereditary cancer care delivery. Over a 5- to 10-year period, 6%-15% of variants undergo reclassification. As the frequency of reclassifications increases, the issue of whether, how, when, and which providers should recontact patients becomes important but remains contentious. METHODS: The authors used...
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