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The Role of HLA-G in Human Papillomavirus Infections and Cervical Carcinogenesis

25 Jun 2020

Abstract excerpt

Human leukocyte antigen (HLA)-G, a non-classical HLA-class I molecule, has a low polymorphism frequency, restricted tissue distribution and immunoinhibitory property. HLA-G expression in tumor cells and cells chronically infected with virus may enable them to escape from host immune surveillance. It is well-known that the HLA-G molecule is a novel biomarker and potential therapeutic target that is relevant in...

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PMID: 32670296
DOI: 10.3389/fimmu.2020.01349

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