Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

GWAS-identified telomere length associated genetic variants predict risk of recurrence of HPV-positive oropharyngeal cancer after definitive radiotherapy.

EBioMedicine - 1 Aug 2023

Sun Peng, Wei Peng, Liu Hongliang, Wu Jia, Gross Neil D, Sikora Andrew G, Wei Qingyi, Shete Sanjay, Zafereo Mark E, Liu Jisheng, Li Guojun

Abstract excerpt

BACKGROUND: Lymphocyte telomere length (LTL)-related genetic variants may modulate LTL and affect recurrence of squamous cell carcinoma of the oropharynx (SCCOP). METHODS: A total of 1013 patients with incident SCCOP were recruited and genotyped for 16 genome-wide association study (GWAS)-identified TL-related polymorphisms. Of these patients, 489 had tumour HPV16 status determination. Univariate and multivariate...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Carcinoma, Squamous Cell
Share to Genome-Wide Association Study

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Head and Neck Neoplasms

Share to Leukocytes

Share to Oropharyngeal Neoplasms

Share to Papillomavirus Infections

Share to Squamous Cell Carcinoma of Head and Neck

Share to Telomere

Source

Open in PubMed Open full text

Identifiers

PMID: 37487414
DOI: 10.1016/j.ebiom.2023.104722
PMCID: PMC10382868

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

GWAS-identified telomere length associated genetic variants predict risk of recurrence of HPV-positive oropharyngeal cancer after definitive radiotherapy.PMID 37487414Read ↗

Genetic variations associated with telomere length predict the risk of recurrence of non-oropharyngeal head and neck squamous cell carcinoma.Semantic proximity Read ↗

TGFβ1 Genetic Variants Predict Clinical Outcomes of HPV-Positive Oropharyngeal Cancer Patients after Definitive Radiotherapy.Semantic proximity Read ↗

Genetic variants in microRNA-binding sites of DNA repair genes as predictors of recurrence in patients with squamous cell carcinoma of the oropharynx.Semantic proximity Read ↗

Genetic variants in TNF-α promoter are predictors of recurrence in patients with squamous cell carcinoma of oropharynx after definitive radiotherapy.Semantic proximity Read ↗

Human Papilloma Virus Associated Oropharyngeal Squamous Cell Carcinoma: Epidemiological and Biological Factors Associated with Local and Distant RecurrenceSemantic proximity Read ↗

Assessing the Relationship Between Leukocyte Telomere Length and Cancer Risk/Mortality in UK Biobank and TCGA Datasets With the Genetic Risk Score and Mendelian Randomization ApproachesSemantic proximity Read ↗

Significance of microRNA-related variants in susceptibility to recurrence of oropharyngeal cancer patients after definitive radiotherapy.Semantic proximity Read ↗

TERT Promoter Mutations Are Enriched in Oral Cavity Cancers and Associated With Locoregional Recurrence.Semantic proximity Read ↗

Apoptotic variants as predictors of risk of oropharyngeal cancer recurrence after definitive radiotherapy.Semantic proximity Read ↗

Relationship between genetically determined telomere length and glioma risk.Semantic proximity Read ↗

Association between miRNA-binding site polymorphisms in double-strand break repair genes and risk of recurrence in patients with squamous cell carcinomas of the non-oropharynx.Semantic proximity Read ↗

A functional variant at miRNA-122 binding site in IL-1a 3' UTR predicts risk of recurrence in patients with oropharyngeal cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.