Article
POLE-mutated Endometrial "Carcinosarcoma".
International journal of gynecological pathology : official journal of the International Society of Gynecological Pathologists - 1 Jan 2025
De Boeck Astrid, Nohr Erik, El-Hallani Soufiane, Ghatage Prafull, Lee Cheng Han, Köbel Martin
Abstract excerpt
The molecular subtype classification of endometrial carcinomas has conceptually changed our approach to this disease. However, open questions remain about how to integrate certain histotype diagnoses with the molecular subtype. We report 2 cases with morphologic suspicion for endometrial carcinosarcoma, that still fell short of the essential criteria for diagnosing carcinosarcoma. On subsequent molecular testing...
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