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[Endometrial adenocarcinoma with mutations in POLE, TP53 genes and microsatellite instability].

Arkhiv patologii - 1 Jan 2024

Chernev A A, Kravtcova E D, Nechushkina V M, Abasov R H, Filipenko M L, Druy A E, Raskin G A

Abstract excerpt

The molecular classification of endometrial cancer developed by The Cancer Genome Atlas project (TCGA, 2013) is currently actively used in gynecological oncology. According to it, endometrial carcinoma is divided into four molecular subtypes: POLE-mutated, MMR deficient (dMMR), TP53-aberrant and unspecified. Endometrial cancer samples belonging to the dMMR and POLE-mutant types are characterized by specific...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 39686898
DOI: 10.17116/patol20248606158

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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