Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort.

doi:10.1371/journal.pone.0302643

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Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort.

PloS one - 1 Jan 2024

Rivara Anna C, Russell Emily M, Carlson Jenna C, Pomer Alysa, Naseri Take, Reupena Muagututia Seifuiva, Manna Samantha L, Viali Satupaitea, Minster Ryan L, Weeks Daniel E, DeLany James P, Kershaw Erin E, McGarvey Stephen T, Hawley Nicola L

Abstract excerpt

BACKGROUND: The A allele of rs373863828 in CREB3 regulatory factor is associated with high Body Mass Index, but lower odds of type 2 diabetes. These associations have been replicated elsewhere, but to date all studies have been cross-sectional. Our aims were (1) to describe the development of type 2 diabetes and change in fasting glucose between 2010 and 2018 among a longitudinal cohort of adult Samoans without...

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PMID: 38829901
DOI: 10.1371/journal.pone.0302643
PMCID: PMC11146712

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