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Article

Genome-wide association analysis reveals potential genetic correlation and causality between circulating inflammatory proteins and amyotrophic lateral sclerosis.

Aging - 30 May 2024

Shen Jing, Gu Xiaochu, Xiao Chenxu, Yan Hanfei, Feng Yu, Li Xiaowei

Abstract excerpt

BACKGROUND: Amyotrophic Lateral Sclerosis (ALS), a fatal neurodegenerative disease, continues to elude complete comprehension of its pathological underpinnings. Recent focus on inflammation in ALS pathogenesis prompts this investigation into the genetic correlation and potential causal relationships between circulating inflammatory proteins and ALS. METHODS: Genome-wide association study (GWAS) data encompassing...

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Identifiers

PMID: 38819224
DOI: 10.18632/aging.205878
PMCID: PMC11210256

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