Article
Serum osteoprotegerin and its gene polymorphisms in patients with Takayasu's arteritis: a bicentric cross-sectional study.
Advances in rheumatology (London, England) - 28 May 2024
Cendon Duran Camila da Silva, de Falco Caparbo Valéria, Santiago Mittermayer Barreto, Hounkpe Bidossessi Wilfried, Pedreira Ana Luisa Souza, de Souza Lima Isabella Vargas, Giardini Henrique Ayres Mayrink, Bonoldi Virgínia Lucia Nazario, Domiciano Diogo Souza, Shinjo Samuel Katsuyuki, Pereira Rosa Maria R
Abstract excerpt
INTRODUCTION: Takayasu's arteritis (TAK) patients are at an elevated risk of metabolic syndrome and cardiovascular diseases (CVD). Currently, there are no well-validated biomarkers to assess this risk in this population. Previous research in different cohorts has linked serum levels of osteoprotegerin (OPG) and its polymorphisms to accelerated atherosclerosis and a marker of poor prognosis in CVD. Thus, we...
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