Article
The interleukin-1 gene cluster polymorphisms are associated with Takayasu's arteritis in Mexican patients.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Jul 2013
Soto López María Elena, Gamboa Ávila Ricardo, Hernández Erick, Huesca-Gómez Claudia, Castrejón-Téllez Vicente, Pérez-Méndez Oscar, Reyes Pedro A, Fragoso-Lona José M, Vargas-Alarcón Gilberto, Cruz-Robles David
Abstract excerpt
Takayasu's arteritis (TA) is a chronic inflammatory arteritis of unknown etiology involving mainly the aorta and its major branches. The interleukin (IL) 1β and IL-1 receptor antagonist have been playing an important role as regulators of inflammation. We investigated whether the polymorphisms at the IL-1B and IL-1RN gene cluster were associated with the genetic susceptibility to develop TA. We analyzed the...
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