Article
Multiple loci associated with indices of renal function and chronic kidney disease.
Nature genetics - 1 Jun 2009
Köttgen Anna, Glazer Nicole L, Dehghan Abbas, Hwang Shih-Jen, Katz Ronit, Li Man, Yang Qiong, Gudnason Vilmundur, Launer Lenore J, Harris Tamara B, Smith Albert V, Arking Dan E, Astor Brad C, Boerwinkle Eric, Ehret Georg B, Ruczinski Ingo, Scharpf Robert B, Chen Yii-Der Ida, de Boer Ian H, Haritunians Talin, Lumley Thomas, Sarnak Mark, Siscovick David, Benjamin Emelia J, Levy Daniel, Upadhyay Ashish, Aulchenko Yurii S, Hofman Albert, Rivadeneira Fernando, Uitterlinden André G, van Duijn Cornelia M, Chasman Daniel I, Paré Guillaume, Ridker Paul M, Kao W H Linda, Witteman Jacqueline C, Coresh Josef, Shlipak Michael G, Fox Caroline S
Abstract excerpt
Chronic kidney disease (CKD) has a heritable component and is an important global public health problem because of its high prevalence and morbidity. We conducted genome-wide association studies (GWAS) to identify susceptibility loci for glomerular filtration rate, estimated by serum creatinine (...
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