Article
Association of eGFR-Related Loci Identified by GWAS with Incident CKD and ESRD.
PLoS genetics - 1 Sept 2011
Böger Carsten A, Gorski Mathias, Li Man, Hoffmann Michael M, Huang Chunmei, Yang Qiong, Teumer Alexander, Krane Vera, O'Seaghdha Conall M, Kutalik Zoltán, Wichmann H-Erich, Haak Thomas, Boes Eva, Coassin Stefan, Coresh Josef, Kollerits Barbara, Haun Margot, Paulweber Bernhard, Köttgen Anna, Li Guo, Shlipak Michael G, Powe Neil, Hwang Shih-Jen, Dehghan Abbas, Rivadeneira Fernando, Uitterlinden André, Hofman Albert, Beckmann Jacques S, Krämer Bernhard K, Witteman Jacqueline, Bochud Murielle, Siscovick David, Rettig Rainer, Kronenberg Florian, Wanner Christoph, Thadhani Ravi I, Heid Iris M, Fox Caroline S, Kao W H
Abstract excerpt
Family studies suggest a genetic component to the etiology of chronic kidney disease (CKD) and end stage renal disease (ESRD). Previously, we identified 16 loci for eGFR in genome-wide association studies, but the associations of these single nucleotide polymorphisms (SNPs) for incident CKD or ESRD are unknown. We thus investigated the association of these loci with incident CKD in 26,308 individuals of European...
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