Article
Mitochondria-related pathogenic genes in acute and chronic kidney disease: a Mendelian randomization study.
Renal failure - 1 Dec 2026
Wang Jia, Yuan TongLing, Wei Qian, Xie Kangping, Zhang Jiong
Abstract excerpt
This study aims to utilize summary-data-based Mendelian randomization (SMR) to explore the potential associations linking mitochondrial-related genes with acute kidney injury (AKI) and chronic kidney disease CKD. This study utilized mitochondrial-related genes from the MitoCarta3.0 database, alongside DNA methylation (mQTLs), gene expression (eQTLs), and protein expression (pQTLs) quantitative trait loci data. We...
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