Article
No Association of Polymorphisms in the Genes Encoding Interleukin-6 and Interleukin-6 Receptor Subunit Alpha with the Risk of Keloids in Polish Patients.
International journal of molecular sciences - 13 May 2024
Dmytrzak Andrzej, Lewandowska Klaudyna, Boroń Agnieszka, Łoniewska Beata, Grzesch Natalie, Brodkiewicz Andrzej, Clark Jeremy S C, Ciechanowicz Andrzej, Kostrzewa-Nowak Dorota
Abstract excerpt
A keloid is a benign fibroproliferative hypertrophy of scar tissue that extends outside the original wound and invades adjacent healthy skin. Keloid formation is thought to be a complex process including overactivity of the interleukin-6 signaling pathway and genetic susceptibility. The aim of the study was to investigate possible associations between rs1800797, rs1800796, and rs1800795 polymorphisms in the...
Read the complete abstract on PubMed