Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CytoSIP: an annotated structural atlas for interactions involving cytokines or cytokine receptors.

Communications biology - 24 May 2024

Wang Lu, Sun Fang, Li Qianying, Ma Haojie, Zhong Juanhong, Zhang Huihui, Cheng Siyi, Wu Hao, Zhao Yanmin, Wang Nasui, Xie Zhongqiu, Zhao Mingyi, Zhu Ping, Zheng Heping

Abstract excerpt

Therapeutic agents targeting cytokine-cytokine receptor (CK-CKR) interactions lead to the disruption in cellular signaling and are effective in treating many diseases including tumors. However, a lack of universal and quick access to annotated structural surface regions on CK/CKR has limited the progress of a structure-driven approach in developing targeted macromolecular drugs and precision medicine...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cytokines
Share to Databases, Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phenotype

Share to Polymorphism, Single Nucleotide

Share to Receptors, Cytokine

Source

Open in PubMed Open full text

Identifiers

PMID: 38789577
DOI: 10.1038/s42003-024-06289-0
PMCID: PMC11126726

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CytoSIP: an annotated structural atlas for interactions involving cytokines or cytokine receptors.PMID 38789577Read ↗

CytoSIP: An annotated structural atlas for interactions involving cytokine or cytokine receptorSemantic proximity Read ↗

Comprehensive characterization of protein-protein interaction network perturbations by human disease mutationsSemantic proximity Read ↗

Interactome INSIDER: a multi-scale structural interactome browser for genomic studiesSemantic proximity Read ↗

KinCytE- a Kinase to Cytokine Explorer to Identify Molecular Regulators and Potential Therapeutic OpportunitiesSemantic proximity Read ↗

TRAIT: A Comprehensive Database for T-cell Receptor–antigen InteractionsSemantic proximity Read ↗

Current status and relevance of single nucleotide polymorphisms in IL-6-/IL-12-type cytokine receptors.Semantic proximity Read ↗

Scop3P-Toolkit: executable structure-aware workflows linking PTMs, peptides, and mutations to protein functionSemantic proximity Read ↗

Disease associated cytokine SNPs database: an annotation and dissemination model.Semantic proximity Read ↗

The structural network of inflammation and cancer: merits and challenges.Semantic proximity Read ↗

Structure of a Janus kinase cytokine receptor complex reveals the basis for dimeric activation.Semantic proximity Read ↗

Structural Analysis of Janus Tyrosine Kinase Variants in Hematological Malignancies: Implications for Drug Development and Opportunities for Novel Therapeutic Strategies.Semantic proximity Read ↗

The structural pathway of interleukin 1 (IL-1) initiated signaling reveals mechanisms of oncogenic mutations and SNPs in inflammation and cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.