Article
The structural network of inflammation and cancer: merits and challenges.
Seminars in cancer biology - 1 Aug 2013
Guven Maiorov Emine, Keskin Ozlem, Gursoy Attila, Nussinov Ruth
Abstract excerpt
Inflammation, the first line of defense against pathogens can contribute to all phases of tumorigenesis, including tumor initiation, promotion and metastasis. Within this framework, the Toll-like receptor (TLR) pathway plays a central role in inflammation and cancer. Although extremely useful, the classical representation of this, and other pathways in the cellular network in terms of nodes (proteins) and edges...
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