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Article

Investigating the causal relationship between thyroid dysfunction diseases and osteoporosis: a two-sample Mendelian randomization analysis.

Scientific reports - 4 Jun 2024

Qi Weihui, Wang Dong, Hong Yihu, Yao Jun, Wang Huang, Zhu Li, Pan Hao

Abstract excerpt

The prevalence of thyroid dysfunction diseases (TDFDs) and osteoporosis (OP) is high. Previous studies have indicated a potential association between TDFDs and OP, yet the causal direction remains unclear. This study aimed to investigate the potential causal relationship between TDFDs and the risk of developing OP and related fractures. We obtained pooled data from genome-wide association studies (GWASs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38834708
DOI: 10.1038/s41598-024-62854-x
PMCID: PMC11150446

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