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The tardigrade-derived mitochondrial abundant heat soluble protein improves adipose-derived stem cell survival against representative stressors

23 May 2024

Abstract excerpt

Human adipose-derived stem cell (ASC) grafts have emerged as a powerful tool in regenerative medicine. However, ASC therapeutic potential is hindered by stressors throughout their use. Here we demonstrate the transgenic expression of the tardigrade-derived mitochondrial abundant heat soluble (MAHS) protein for improved ASC resistance to metabolic, mitochondrial, and injection shear stress. In vitro,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 38783150
DOI: 10.1038/s41598-024-62693-w

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