Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Temporal heterogeneity in single-cell gene expression and mechanical properties during adipogenic differentiation.

Journal of biomechanics - 13 Apr 2015

Labriola Nicholas R, Darling Eric M

Abstract excerpt

Adipose-derived stem/stromal cells (ASCs) respond heterogeneously when exposed to lineage-specific induction medium. Variable responses at the single-cell level can be observed in the production of lineage-specific metabolites, expression of mRNA transcripts, and adoption of mechanical phenotypes. Understanding the relationship between the biological and mechanical characteristics for individual ASCs is crucial...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adipocytes
Share to Adipogenesis
Share to Adipose Tissue

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Biomechanical Phenomena

Share to Cytoskeleton

Share to Genetic Heterogeneity

Share to Microscopy, Atomic Force

Share to PPAR gamma

Source

Open in PubMed Open full text

Identifiers

PMID: 25683518
DOI: 10.1016/j.jbiomech.2015.01.033
PMCID: PMC4380682

Genes

PPARG
AFM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Temporal heterogeneity in single-cell gene expression and mechanical properties during adipogenic differentiation.PMID 25683518Read ↗

Single-cell profiling reveals the origin of phenotypic variability in adipogenesis.Semantic proximity Read ↗

Immunophenotyping and transcriptional profiling of in vitro cultured human adipose tissue derived stem cells.Semantic proximity Read ↗

Expression analysis of human adipose-derived stem cells during in vitro differentiation to an adipocyte lineage.Semantic proximity Read ↗

Single-Cell Transcriptomic Sequencing Analyses of Cell Heterogeneity During Osteogenesis of Human Adipose-Derived Mesenchymal Stem CellsSemantic proximity Read ↗

Monolayer cell expansion conditions affect the chondrogenic potential of adipose‐derived stem cellsSemantic proximity Read ↗

On the origin and impact of mesenchymal stem cell heterogeneity: new insights and emerging tools for single cell analysisSemantic proximity Read ↗

Characterization of directed differentiation by high-throughput single-cell RNA-SeqSemantic proximity Read ↗

Plasticity in adipogenesis and osteogenesis of human mesenchymal stem cellsSemantic proximity Read ↗

Single-cell RNA sequencing reveals the heterogeneity of adipose tissue-derived mesenchymal stem cells under chondrogenic inductionSemantic proximity Read ↗

Mechanobiology: A landscape for reinterpreting stem cell heterogeneity and regenerative potential in diseased tissuesSemantic proximity Read ↗

Characterization of Mechanics Driven Heterogeneity in Mesenchymal Stromal CellsSemantic proximity Read ↗

Electrical signature of heterogeneous human mesenchymal stem cellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.