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Article

[Incidence of common gene mutations in early-onset colorectal cancer and the association with cancer survival: a meta-analysis].

Zhonghua wei chang wai ke za zhi = Chinese journal of gastrointestinal surgery - 25 May 2024

Zhang R Q, Li S H, Hu T J, Xu L Y, Zhu Y S, Li X

Abstract excerpt

Objective: The incidence of early-onset colorectal cancer (EOCRC) is increasing globally; however, the molecular characteristics and prognosis of sporadic EOCRC are unclear. In this systematic review and meta-analysis, we aimed to investigate the incidence of gene mutations and their association with cancer survival in sporadic EOCRC, focusing on six common gene mutations (TP53, BRAF, KRAS, NRAS, PTEN, and APC)....

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Identifiers

PMID: 38778689
DOI: 10.3760/cma.j.cn441530-20240304-00083

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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