Article
Genetic determinants of glycated hemoglobin levels in the Greenlandic Inuit population.
European journal of human genetics : EJHG - 1 Jun 2018
Appel Emil V R, Moltke Ida, Jørgensen Marit E, Bjerregaard Peter, Linneberg Allan, Pedersen Oluf, Albrechtsen Anders, Hansen Torben, Grarup Niels
Abstract excerpt
We previously showed that a common genetic variant leads to a remarkably increased risk of type 2 diabetes (T2D) in the small and historically isolated Greenlandic population. Motivated by this, we aimed at discovering novel genetic determinants for glycated hemoglobin (HbA1C) and at estimating the effect of known HbA1C-associated loci in the Greenlandic population. We analyzed genotype data from 4049...
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