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Article

Molecular mechanism of choline and ethanolamine transport in humans.

Nature - 1 Jun 2024

Ri Keiken, Weng Tsai-Hsuan, Claveras Cabezudo Ainara, Jösting Wiebke, Zhang Yu, Bazzone Andre, Leong Nancy C P, Welsch Sonja, Doty Raymond T, Gursu Gonca, Lim Tiffany Jia Ying, Schmidt Sarah Luise, Abkowitz Janis L, Hummer Gerhard, Wu Di, Nguyen Long N, Safarian Schara

Abstract excerpt

Human feline leukaemia virus subgroup C receptor-related proteins 1 and 2 (FLVCR1 and FLVCR2) are members of the major facilitator superfamily1. Their dysfunction is linked to several clinical disorders, including PCARP, HSAN and Fowler syndrome2-7. Earlier studies concluded that FLVCR1 may function as a haem exporter8-12, whereas FLVCR2 was suggested to act as a haem importer13, yet conclusive biochemical and...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 38778100
DOI: 10.1038/s41586-024-07444-7
PMCID: PMC11168923

Genes

FLVCR1
FLVCR2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Molecular mechanism of choline and ethanolamine transport in humans.PMID 38778100Read ↗

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