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Article

Exploration of deleterious single nucleotide polymorphisms in the components of human P bodies: an in silico approach.

Gene - 10 Oct 2013

Venkatesh Thejaswini, Suresh Padmanaban S

Abstract excerpt

P bodies are 100-300 nm sized organelles involved in mRNA silencing and degradation. A total of 60 human proteins have been reported to localize to P bodies. Several human SNPs contribute to complex diseases by altering the structure and function of the proteins. Also, SNPs alter various transcription factors binding, splicing and miRNA regulatory sites. Owing to the essential functions of P bodies in mRNA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23892092
DOI: 10.1016/j.gene.2013.07.010

Genes

DCP2
GEMIN5
STAU1
TRIM71
XRN1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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