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Article

AIOLOS-Associated Inborn Errors of Immunity.

Journal of clinical immunology - 22 May 2024

Yamashita Motoi, Morio Tomohiro

Abstract excerpt

AIOLOS, encoded by the IKZF3 gene, belongs to the Ikaros zinc finger transcription factor family and plays a pivotal role in regulating lymphocyte development. Recently, heterozygous missense loss-of-function variants within the DNA-binding domain of the IKZF3 gene (G159R, N160S, and G191R) have been identified in patients with inborn errors of immunity (IEI). Additionally, a missense and a truncating variant...

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Identifiers

PMID: 38773004
DOI: 10.1007/s10875-024-01730-9
PMCID: PMC11108880

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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