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Article

DNA sequence properties that predict susceptibility to epiallelic switching.

The EMBO journal - 1 Mar 2017

Catoni Marco, Griffiths Jayne, Becker Claude, Zabet Nicolae Radu, Bayon Carlos, Dapp Mélanie, Lieberman-Lazarovich Michal, Weigel Detlef, Paszkowski Jerzy

Abstract excerpt

Transgenerationally heritable epialleles are defined by the stable propagation of alternative transcriptional states through mitotic and meiotic cell cycles. Given that the propagation of DNA methylation at CpG sites, mediated in Arabidopsis by MET1, plays a central role in epigenetic inheritance, we examined genomewide DNA methylation in partial and complete loss-of-function met1 mutants. We interpreted the data...

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Arabidopsis
Arabidopsis Proteins
DNA (Cytosine-5-)-Methyltransferases
DNA Methylation
DNA, Plant

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Epigenesis, Genetic

Gene Expression Regulation, Plant

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Identifiers

PMID: 28069706
DOI: 10.15252/embj.201695602
PMCID: PMC5331756

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