Article
Haplotype determination of the Bombyx mori nucleopolyhedrovirus by Nanopore sequencing and linkage of single nucleotide variants.
The Journal of general virology - 1 May 2024
Wennmann Jörg T, Lim Fang-Shiang, Senger Sergei, Gani Mudasir, Jehle Johannes A, Keilwagen Jens
Abstract excerpt
Naturally occurring isolates of baculoviruses, such as the Bombyx mori nucleopolyhedrovirus (BmNPV), usually consist of numerous genetically different haplotypes. Deciphering the different haplotypes of such isolates is hampered by the large size of the dsDNA genome, as well as the short read length of next generation sequencing (NGS) techniques that are widely applied for baculovirus isolate characterization. In...
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