Article
Ultra Deep Sequencing of a Baculovirus Population Reveals Widespread Genomic Variations.
Viruses - 7 Jul 2015
Chateigner Aurélien, Bézier Annie, Labrousse Carole, Jiolle Davy, Barbe Valérie, Herniou Elisabeth A
Abstract excerpt
Viruses rely on widespread genetic variation and large population size for adaptation. Large DNA virus populations are thought to harbor little variation though natural populations may be polymorphic. To measure the genetic variation present in a dsDNA virus population, we deep sequenced a natural strain of the baculovirus Autographa californica multiple nucleopolyhedrovirus. With 124,221X average genome coverage...
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