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Article

Association of lipid-lowering drug targets with risk of cutaneous melanoma: a mendelian randomization study.

BMC cancer - 17 May 2024

Miao Lusheng, Miao Taosheng, Zhang Ying, Hao Jin

Abstract excerpt

BACKGROUND: Melanoma proliferation is partly attributed to dysregulated lipid metabolism. The effectiveness of lipid-lowering drugs in combating cutaneous melanoma (CM) is a subject of ongoing debate in both in vitro and clinical studies. METHOD: This study aims to evaluate the causal relationship between various lipid-lowering drug targets, namely 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR, targeted...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 38760735
DOI: 10.1186/s12885-024-12366-8
PMCID: PMC11102253

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