Article
Polyunsaturated fatty acids and risk of melanoma: A Mendelian randomisation analysis.
International journal of cancer - 1 Aug 2018
Liyanage Upekha E, Law Matthew H, Ong Jue Sheng, Cust Anne E, Mann Graham J, Ward Sarah V, Gharahkhani Puya, Iles Mark M, MacGregor Stuart
Abstract excerpt
Melanoma is the deadliest form of skin cancer, mainly affecting populations of European ancestry. Some observational studies suggest that particular diets reduce melanoma risk, putatively through an increase in polyunsaturated fatty acid (PUFA) consumption. However, interpretation of these observational findings is difficult due to residual confounding or reverse causality. To date, a randomized controlled trial...
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