Article
Basal forebrain volume and metabolism in carriers of the Colombian mutation for autosomal dominant Alzheimer's disease.
Scientific reports - 17 May 2024
Teipel Stefan, Grazia Alice, Dyrba Martin, Grothe Michel J, Pomara Nunzio
Abstract excerpt
We aimed to study atrophy and glucose metabolism of the cholinergic basal forebrain in non-demented mutation carriers for autosomal dominant Alzheimer's disease (ADAD). We determined the level of evidence for or against atrophy and impaired metabolism of the basal forebrain in 167 non-demented carriers of the Colombian PSEN1 E280A mutation and 75 age- and sex-matched non-mutation carriers of the same kindred...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
